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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK1 All Species: 26.97
Human Site: S100 Identified Species: 49.44
UniProt: Q9P0L2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0L2 NP_061120.3 795 89003 S100 K T Q L N P T S L Q K L F R E
Chimpanzee Pan troglodytes XP_001172839 796 89049 S100 K T Q L N P T S L Q K L F R E
Rhesus Macaque Macaca mulatta XP_001115611 778 86745 I103 K L F R E V R I M K V L N H P
Dog Lupus familis XP_536123 782 87409 K99 F R E V R I M K I L N H P N I
Cat Felis silvestris
Mouse Mus musculus Q8VHJ5 795 88528 S100 K T Q L N P T S L Q K L F R E
Rat Rattus norvegicus O08678 793 88216 S100 K T Q L N P T S L Q K L F R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511751 793 88836 S99 K T Q L N P T S L Q K L F R E
Chicken Gallus gallus Q9IA88 798 88848 L98 V M E T K D M L Y I V T E F A
Frog Xenopus laevis NP_001085126 792 88624 S100 K T Q L N P T S L Q K L F R E
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 N99 K T Q L D D E N L K K I F R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S210 K T A L N P S S L Q K L F R E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671
Baker's Yeast Sacchar. cerevisiae P06782 633 72027
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 68.9 95.9 N.A. 94.9 94.3 N.A. 92.8 30.4 88.6 27.8 N.A. N.A. N.A. 40.7 N.A.
Protein Similarity: 100 99.3 80.2 96.8 N.A. 97.3 96.9 N.A. 95.9 51.3 94.2 44 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 100 100 13.3 0 N.A. 100 100 N.A. 100 0 100 60 N.A. N.A. N.A. 86.6 N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 100 100 N.A. 100 6.6 100 86.6 N.A. N.A. N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.9 28 N.A.
Protein Similarity: N.A. N.A. N.A. 44.4 46.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 16 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 16 0 8 0 8 0 0 0 0 0 8 0 62 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 62 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % H
% Ile: 0 0 0 0 0 8 0 8 8 8 0 8 0 0 8 % I
% Lys: 70 0 0 0 8 0 0 8 0 16 62 0 0 0 0 % K
% Leu: 0 8 0 62 0 0 0 8 62 8 0 62 0 0 0 % L
% Met: 0 8 0 0 0 0 16 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 54 0 0 8 0 0 8 0 8 8 0 % N
% Pro: 0 0 0 0 0 54 0 0 0 0 0 0 8 0 8 % P
% Gln: 0 0 54 0 0 0 0 0 0 54 0 0 0 0 0 % Q
% Arg: 0 8 0 8 8 0 8 0 0 0 0 0 0 62 0 % R
% Ser: 0 0 0 0 0 0 8 54 0 0 0 0 0 0 0 % S
% Thr: 0 62 0 8 0 0 47 0 0 0 0 8 0 0 0 % T
% Val: 8 0 0 8 0 8 0 0 0 0 16 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _